After years of mounting losses, companies like Sharp, Sony and Panasonic finally appear to be grappling with the malaise that has cost them their leading edge in consumer electronics.
Vaccines[ edit ] Medically important vaccines developed at Merck include the first mumps vaccine the first rubella vaccine and the first trivalent measles, mumps, rubella MMR vaccine each of which was developed by Merck scientist Maurice Hilleman.
The incidence of rubella-associated birth defects fell from up to 10, per year in the U.
Baer, and Frederick C. Novello of Merck and Co. Antibacterials[ edit ] Streptomycin, discovered during a Merck-funded research program in Selman Waksman's laboratory at Rutgers University inbecame the first effective treatment for tuberculosis.
The university then set up non-exclusive licenses with seven companies to ensure a reliable supply of the antibiotic. Antibiotics of the carbapenem class play an important role in treatment guidelines for certain hospital-acquired and multi-drug resistant infections.
Vioxx was designed as a selective inhibitor of the enzyme cyclooxygenase Such compounds were expected to cause less gastrointestinal bleeding than older anti-inflammatory drugs such as naproxenwhich were associated with 20, hospitalizations and deaths each year.
Merck adjusted the labeling of Vioxx to reflect possible cardiovascular risks in An analysis for the periodbased on U. Medical Expenditure Survey data, reported that Vioxx was associated with 46, heart attacks, and along with the other popular COX-2 inhibitor Celebrexan estimated 26, deaths from both.
Merck has refused to consider compensation for Vioxx victims and their families outside the US. This is particularly true in the UK where there are at least victims and the legal protection afforded to the victims and their families is particularly weak.
A Stanford Medical School professor said that Merck was engaged in intimidation of researchers and infringement upon academic freedom. Up to that point, the World Health Organization had fought the disease through the use of insecticides to lower the population of its primary vector, the Black Fly.
Merck's involvement is considered a key factor in the success against the disease all over the world,  and the decision to donate the entirety of the drug to all those in need of it is used as part of the Mectizan Donation Program that covers countries such as Yemen and African countries.
Blindness caused by onchocerciasis is decreasing, and there are regions of Latin America and Africa that have been shown to have completely eliminated the disease altogether. Prior to the settlement, Merck had prevailed in 3 of 5 so-called bellwether trials. Approximately cases still await adjudiction or settlement as of August Although it gave the appearance of being an independent peer-reviewed journal, without any indication that Merck had paid for it, the journal actually reprinted articles that originally appeared in other publications and that were favorable to Merck.
The misleading publication came to light in during a personal injury lawsuit filed over Vioxx; 9 of 29 articles in the journal's second issue referred positively to Vioxx.
Current projects include the development of low cost, thermostable vaccines for the prevention of cholera, rotavirus, and meningitis.
The settlement was one of the largest pharmaceutical settlements in history.
Merck chemists and engineers subsequently replaced the compound with others having fewer negative environmental effects. Merck has also modified its equipment to protect the environment, installing a distributed control system that coordinates chemical reactions more efficiently and expedites manufacturing by 50 percent, eliminating the need for the disposal and storage of harmful waste.
Biological oxygen demand has also been reduced.Force through Reforms. This annual report contains certain statements describing the future plans, strategies and performance of Sharp Corporation and its consolidated subsidiaries (hereinafter “Sharp”).
These statements are not based on historical or present fact, but rather our business in Europe, reduce company-wide costs, and. Faced with major losses from operations, Sharp Corporation’s president, Mikio Katayama, questioned the whether it was necessary to reform the current business operating model.
Sharp’s current operating model contained several flaws. Sharp Corporation () - Financial and Strategic SWOT Analysis Review -provides you an in-depth strategic SWOT analysis of the company’s businesses and operations.
The profile has been compiled by GlobalData to bring to you a clear and an unbiased view of the company’s key strengths and weaknesses and the potential opportunities and threats.
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Words: Pages: 7. Open Document. Changing operating model from vertical integration to horizontal integration for the company’s production technologies and manufacturing capabilities will give it a better standing in the competitive market. Forming alliances with local companies in.
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